A MSN-based tumor-targeted nanoplatform to interfere with lactate metabolism to induce tumor cell acidosis for tumor suppression and anti-metastasis
Zhaoxia Chen, Miao‐Deng Liu, Deng‐Ke Guo, Mei‐Zhen Zou, Shibo Wang, Han Cheng, Zhenlin Zhong, Xian‐Zheng Zhang
Abstract
A tumor targeting drug delivery system was designed to interfere with lactate metabolism for tumor therapy and anti-metastasis research.
Topics & Concepts
MetastasisTumor cellsCancer researchMetabolismAcidosisChemistryCellMedicineInternal medicineBiochemistryCancerCancer, Hypoxia, and MetabolismAmino Acid Enzymes and MetabolismNanoplatforms for cancer theranostics