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Surgical margins in head and neck squamous cell carcinoma: A narrative review

Yang Chen, Nian‐Nian Zhong, Lei‐Ming Cao, Bing Liu, Lin‐Lin Bu

2024International Journal of Surgery43 citationsDOIOpen Access PDF

Abstract

Head and neck squamous cell carcinoma (HNSCC), a prevalent and frequently recurring malignancy, often necessitates surgical intervention. The surgical margin (SM) plays a pivotal role in determining the postoperative treatment strategy and prognostic evaluation of HNSCC. Nonetheless, the process of clinical appraisal and assessment of the SMs remains a complex and indeterminate endeavor, thereby leading to potential difficulties for surgeons in defining the extent of resection. In this regard, we undertake a comprehensive review of the suggested surgical distance in varying circumstances, diverse methods of margin evaluation, and the delicate balance that must be maintained between tissue resection and preservation in head and neck surgical procedures. This review is intended to provide surgeons with pragmatic guidance in selecting the most suitable resection techniques, and in improving patients' quality of life by achieving optimal functional and aesthetic restoration.

Topics & Concepts

MedicineHead and neck squamous-cell carcinomaHead and neckNarrative reviewMalignancyBasal cellSurgerySurgical marginMargin (machine learning)ResectionHead and neck cancerGeneral surgeryIntensive care medicinePathologyRadiation therapyComputer scienceMachine learningHead and Neck Cancer StudiesReconstructive Surgery and Microvascular TechniquesHead and Neck Surgical Oncology
Surgical margins in head and neck squamous cell carcinoma: A narrative review | Litcius