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Methionine synthase is essential for cancer cell proliferation in physiological folate environments

Mark R. Sullivan, Alicia M. Darnell, Montana F. Reilly, Tenzin Kunchok, Lena Joesch-Cohen, Daniel W. Rosenberg, Ahmed Ali, Matthew G. Rees, Jennifer A. Roth, Caroline A. Lewis, Matthew G. Vander Heiden

2021Nature Metabolism106 citationsDOIOpen Access PDF

Topics & Concepts

Methionine synthaseMethionineHomocysteineCell growthBiochemistryChemistryBiologyCell biologyAmino acidFolate and B Vitamins ResearchCancer Research and TreatmentsAmino Acid Enzymes and Metabolism
Methionine synthase is essential for cancer cell proliferation in physiological folate environments | Litcius