Hsa-miR-34a-5p reverses multidrug resistance in gastric cancer cells by targeting the 3′-UTR of SIRT1 and inhibiting its expression
Xiaojing Deng, Hailun Zheng, Xiquan Ke, Min Deng, Zhiquan Ma, Yu Zhu, Yingying Cui
Topics & Concepts
Multiple drug resistanceP-glycoproteinApoptosisSirtuin 1Cancer researchmicroRNAChemotherapyIn vivoCancerCancer cellDrug resistanceBiologyDownregulation and upregulationThree prime untranslated regionUntranslated regionPharmacologyChemistryMedicineMessenger RNAGeneInternal medicineBiochemistryMicrobiologyBiotechnologyMicroRNA in disease regulationRNA Interference and Gene DeliveryRNA modifications and cancer