Investigation of the interactions between flavonoids and human organic anion transporting polypeptide 1B1 using fluorescent substrate and 3D-QSAR analysis
Yiqun Xiang, Shuai Liu, Jingjie Yang, Zhongmin Wang, Hongjian Zhang, Chunshan Gui
Topics & Concepts
ChemistryQuantitative structure–activity relationshipFlavonesFlavonolsHydrogen bondStereochemistrySubstrate (aquarium)FlavonoidBiochemistryOrganic chemistryAntioxidantChromatographyMoleculeBiologyEcologyDrug Transport and Resistance MechanismsProtein Interaction Studies and Fluorescence AnalysisDrug-Induced Hepatotoxicity and Protection