Potential role of statins in COVID-19
Ken Cheah Hooi Lee, Duu Wen Sewa, Ghee Chee Phua
Abstract
Patients with COVID-19 infection have an increased risk of cardiovascular complications and thrombotic events. Statins are known for their pleiotropic anti-inflammatory, antithrombotic and immunomodulatory effects. They may have a potential role as adjunctive therapy to mitigate endothelial dysfunction and dysregulated inflammation in patients with COVID-19 infection.
Topics & Concepts
AntithromboticCoronavirus disease 2019 (COVID-19)MedicineInflammation2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Endothelial dysfunctionIntensive care medicineImmunologyInternal medicineVirologyDiseaseInfectious disease (medical specialty)OutbreakCOVID-19 Clinical Research StudiesLipoproteins and Cardiovascular HealthInflammasome and immune disorders