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A small-molecule inhibitor of MDMX suppresses cervical cancer cells via the inhibition of E6-E6AP-p53 axis

Jingwen Zhang, Guohua Yu, Yanting Yang, Yingjie Wang, Mengqi Guo, Qikun Yin, Chunhong Yan, Jingwei Tian, Fenghua Fu, Hongbo Wang

2022Pharmacological Research37 citationsDOI

Topics & Concepts

MDMXHeLaCarcinogenesisMdm2Cancer researchUbiquitin ligaseCisplatinChemistryUbiquitinApoptosisCervical cancerCancerIn vivoIn vitroBiologyMedicineChemotherapyInternal medicineBiochemistryGeneBiotechnologyCancer-related Molecular PathwaysUbiquitin and proteasome pathwaysEpigenetics and DNA Methylation
A small-molecule inhibitor of MDMX suppresses cervical cancer cells via the inhibition of E6-E6AP-p53 axis | Litcius