Inhibition of USP14 Suppresses ROS-dependent Ferroptosis and Alleviates Renal Ischemia/Reperfusion Injury
Jie Pan, Jing Zhao, Ling Feng, Xiaoli Xu, Zhiting He, Wei Liang
Topics & Concepts
Deubiquitinating enzymeOxidative stressReactive oxygen speciesAcute kidney injuryKidneyReperfusion injuryChemistryIn vivoRenal ischemiaIschemiaProgrammed cell deathMolecular biologyPharmacologyUbiquitinMedicineBiologyBiochemistryApoptosisInternal medicineGeneBiotechnologyFerroptosis and cancer prognosisEpigenetics and DNA MethylationHeme Oxygenase-1 and Carbon Monoxide