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Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome

Rosaura Esteve‐Puig, Fina Climent, David Piñeyro, Eva Domingo‐Doménech, Verónica Dávalos, Maite Encuentra, Anna Rea, Nadia Espejo‐Herrera, Marta Soler, Miguel Lopez, Vanessa Ortiz-Barahona, Gustavo Tapia, José‐Tomás Navarro, Joan Cid, Lourdes Farré, Alberto Villanueva, Isolda Casanova, Ramón Mangues, Pablo Santamarina‐Ojeda, Agustín F. Fernández, Mario F. Fraga, Miguel Á. Piris, Nitzan Kol, Chen Avrahami, Sharon Moshitch-Moshkovitz, Gideon Rechavi, Anna Sureda, Manel Esteller

2020Blood58 citationsDOIOpen Access PDF

Abstract

We thank CERCA Programme/Generalitat de Catalunya for institutional support. This work was supported by the Health Department PERIS-project no. SLT/002/16/00374 and AGAUR-projects no. 2017SGR1080 of the Catalan Government (Generalitat de Catalunya); Ministerio de Ciencia e Innovación (MCI), Agencia Estatal de Investigación (AEI) and European Regional Development Fund (ERDF) project no. RTI2018-094049-B-I00; the Cellex Foundation; and “la Caixa” Banking Foundation (LCF/PR/GN18/51140001). P.S.O. is a fellow of the Severo Ochoa Program (Bp17-
\n165). V.D. is supported by the Spanish Association Against Cancer (AECC).

Topics & Concepts

CatalanEuropean unionGovernment (linguistics)MedicinePolitical scienceOncologyHumanitiesBusinessEconomic policyLinguisticsPhilosophyRNA modifications and cancerEpigenetics and DNA MethylationCancer-related gene regulation
Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome | Litcius