COVID-19–Associated Bifacial Weakness with Paresthesia Subtype of Guillain-Barré Syndrome
Katherine L. Hutchins, Jaclyn H. Jansen, Adam D. Comer, Richard V. Scheer, Greg Zahn, Alisha E. Capps, Lynn Weaver, Nicholas A. Koontz
Abstract
We report a case of bifacial weakness with paresthesia, a recognized Guillain-Barré syndrome subtype characterized by rapidly progressive facial weakness and paresthesia without ataxia or other cranial neuropathies, which was temporally associated with antecedent coronavirus 2019 (COVID-19). This case highlights a potentially novel but critically important neurologic association of the COVID-19 disease process. Herein, we detail the clinicoradiologic work-up and diagnosis, clinical course, and multidisciplinary medical management of this patient with COVID-19. This case is illustrative of the increasingly recognized but potentially underreported neurologic manifestations of COVID-19, which must be considered and further investigated in this pandemic disease.