Litcius/Paper detail

Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes

Parisha P. Shah, Wenjian Lv, Joshua H. Rhoades, Andrey Poleshko, Deepti Abbey, Matthew A. Caporizzo, Ricardo Linares-Saldana, Julie Heffler, Nazish Sayed, Dilip Thomas, Qiaohong Wang, L. Stanton, Kenneth Bedi, Michael P. Morley, Thomas P. Cappola, Anjali Owens, Kenneth B. Margulies, David B. Frank, Joseph C. Wu, Daniel J. Rader, Wenli Yang, Benjamin L. Prosser, Kiran Musunuru, Rajan Jain

2021Cell stem cell142 citationsDOIOpen Access PDF

Topics & Concepts

LMNALaminBiologyNuclear laminaChromatinPhenotypeEpigeneticsCell biologyGeneticsInduced pluripotent stem cellGeneNuclear proteinTranscription factorEmbryonic stem cellNuclear Structure and FunctionGenomics and Chromatin DynamicsRNA Research and Splicing