Litcius/Paper detail

Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP

Yi Zhou, Mingjian Fei, Gu Zhang, Wei‐Ching Liang, WeiYu Lin, Yan Wu, Robert Piskol, John Brady Ridgway, Erin McNamara, Haochu Huang, Juan Zhang, Jaehak Oh, Jaina M. Patel, Diana Jakubiak, Jeffrey Lau, Beth Blackwood, Daniel D. Bravo, Yongchang Shi, Jianyong Wang, Hong‐Ming Hu, Wyne P. Lee, Rajiv Jesudason, Dewakar Sangaraju, Zora Modrušan, Keith R. Anderson, Søren Warming, Merone Roose‐Girma, Minhong Yan

2020Immunity402 citationsDOIOpen Access PDF

Topics & Concepts

MERTKEfferocytosisImmune systemBiologyExtracellularBlockadeCancer researchInflammationApoptosisCancer immunotherapyCell biologyReceptorImmunologyMacrophageImmunotherapySignal transductionReceptor tyrosine kinaseBiochemistryIn vitroPhagocytosis and Immune RegulationAdenosine and Purinergic SignalingImmune cells in cancer