Knockdown of HDAC6 alleviates ventricular remodeling in experimental dilated cardiomyopathy via inhibition of NLRP3 inflammasome activation and promotion of cardiomyocyte autophagy
Xuefeng Pang, Qigang Guan, Xue Lin, Ning Chang
Topics & Concepts
AutophagyGene knockdownGene silencingHDAC6InflammasomeCell biologyIn vivoCancer researchSmall hairpin RNAPyroptosisBiologyChemistryApoptosisImmunologyInflammationHistone deacetylaseHistoneGeneBiochemistryBiotechnologyAutophagy in Disease and TherapyHistone Deacetylase Inhibitors ResearchPeptidase Inhibition and Analysis