Novel N(SCF <sub>3</sub> )(CF <sub>3</sub> )-amines: synthesis, scalability and stability
Yi Yang, Nathalie Saffon‐Merceron, Julien C. Vantourout, Anis Tlili
Abstract
-(trifluoromethyl) amines using a combination of isothiocyanates with a fluoride source and an electrophilic trifluoromethylthiolation reagent. More interestingly, the scalability of the methodology has been demonstrated and the stability of the new motif has been studied.
Topics & Concepts
ReagentTrifluoromethylElectrophileScalabilityChemistryThio-Combinatorial chemistryFluorideStereochemistryOrganic chemistryComputer scienceCatalysisInorganic chemistryDatabaseAlkylFluorine in Organic ChemistrySynthesis and Biological EvaluationSulfur-Based Synthesis Techniques