CD25-Treg-depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity
Isabelle Solomon, Maria Amann, Anne Goubier, Frederick Arce Vargas, Dimitrios Zervas, Qing Chen, Jake Y. Henry, Ehsan Ghorani, Ayse U. Akarca, Teresa Marafioti, Anna Śledzińska, Mariana Werner Sunderland, Dafne Franz Demane, Joanne Ruth Clancy, Andrew Georgiou, Josephine Salimu, Pascal Merchiers, Mark Brown, Reto Flury, Jan Eckmann, Claudio Murgia, Johannes Sam, Björn Jacobsen, Estelle Marrer‐Berger, Christophe Boetsch, Sara Belli, Lea Leibrock, J. Benz, Hans Koll, Roger P.M. Sutmuller, Karl S. Peggs, Sergio A. Quezada
Topics & Concepts
IL-2 receptorEffectorAntibodyImmunologyImmune systemBiologyImmunotherapyCancer researchBlocking antibodyT cellImmune Cell Function and InteractionT-cell and B-cell ImmunologyImmunotherapy and Immune Responses