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Astaxanthin nanoparticles ameliorate dextran sulfate sodium-induced colitis by alleviating oxidative stress, regulating intestinal flora, and protecting the intestinal barrier

Mengfan Luo, Qiaoyue Yuan, Mingzhen Liu, Xingye Song, Yingjie Xu, Tao Zhang, Xiaoqun Zeng, Zhen Wu, Daodong Pan, Yuxing Guo

2023Food & Function19 citationsDOI

Abstract

This study aimed to develop a novel astaxanthin nanoparticle using gum arabic (GA) and whey protein powder enriched with milk fat globule membranes (MFGM-WPI) as carriers and to investigate its effect and alleviation mechanism on colitis in mice.

Topics & Concepts

AstaxanthinOxidative stressColitisGum arabicChemistryDextranGum acaciaWhey protein isolateMicrobiologyWhey proteinFood scienceBiochemistryBiologyImmunologyCarotenoidProteins in Food SystemsProbiotics and Fermented FoodsFood composition and properties
Astaxanthin nanoparticles ameliorate dextran sulfate sodium-induced colitis by alleviating oxidative stress, regulating intestinal flora, and protecting the intestinal barrier | Litcius