Single-atom replacement as a general approach towards visible-light/near-infrared heavy-atom-free photosensitizers for photodynamic therapy
Juan Tang, Lushun Wang, Axel Loredo, Carson C. Cole, Han Xiao
Abstract
Thio-based photosensitizer: a general strategy for preparing visible/NIR light absorbing heavy-atom-free photosensitizers was developed by performing a simple sulfur-for-oxygen atom substitution within existing fluorescent molecules.
Topics & Concepts
Singlet oxygenPhotodynamic therapyPhototoxicityPhotochemistryChemistryFluorophoreConjugated systemQuantum yieldVisible spectrumReactive oxygen speciesChromophoreOxygenCombinatorial chemistryFluorescenceMaterials scienceOptoelectronicsOrganic chemistryIn vitroPolymerOpticsPhysicsBiochemistryNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesPorphyrin and Phthalocyanine Chemistry