Human milk oligosaccharides 2′-fucosyllactose and 3-fucosyllactose attenuate ovalbumin-induced food allergy through immunoregulation and gut microbiota modulation
Siya Wu, Haiqin Chen, Renqiang Yu, Huizhen Li, Jianxin Zhao, Catherine Stanton, R. Paul Ross, Wei Chen, Bo Yang
Abstract
2′-FL and 3-FL may modulate immunity by modulating the gut microbiota, increasing the content of short-chain fatty acids, and enhancing the intestinal barrier function, thus attenuating OVA-induced allergic symptoms.
Topics & Concepts
OvalbuminAllergyFood allergyMicrobiologyGut floraImmunologyAllergic responseBiologyChemistryAntibodyImmune systemImmunoglobulin EInfant Nutrition and HealthInfant Health and DevelopmentBreastfeeding Practices and Influences