Design, synthesis and evaluation of carbazole derivatives as potential antimicrobial agents
Yijie Xue, Mingyue Li, Xuejun Jin, Chang‐Ji Zheng, Hu‐Ri Piao
Abstract
binding to dihydrofolate reductase might account for the antimicrobial effect.
Topics & Concepts
AntimicrobialChemistryDihydrofolate reductaseSemicarbazideCarbazoleMoietyEnzymeIn vitroDocking (animal)StereochemistryCell cultureMultiple drug resistanceLead compoundBiochemistryPharmacologyAntibioticsBiologyOrganic chemistryNursingGeneticsMedicineSynthesis and biological activityCancer therapeutics and mechanismsFungal Plant Pathogen Control