A neutrophil cell membrane-biomimetic nanoplatform based on <scp>l</scp>-arginine nanoparticles for early osteoarthritis diagnosis and nitric oxide therapy
Qianqian Yu, Yuqin Huang, Xu Chen, Yutong Chen, Xufeng Zhu, Yanan Liu, Jie Liu
Abstract
studies demonstrated that NM-LANPs@Ru effectively targeted inflamed OA, based on real-time dual-modal FL/PA imaging, eventually exhibiting its excellent anti-inflammatory activity. Our study may provide a new approach for the early diagnosis and treatment of osteoarthritis using a neutrophil-cell-membrane-based biomimetic nanoplatform for NO or drug delivery.
Topics & Concepts
Nitric oxideOsteoarthritisNanoparticleMembraneCellChemistryMedicineMaterials scienceBiophysicsNanotechnologyBiochemistryPathologyBiologyInternal medicineAlternative medicineNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisMolecular Sensors and Ion Detection