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Gbx2 Identifies Two Amacrine Cell Subtypes with Distinct Molecular, Morphological, and Physiological Properties

Patrick C. Kerstein, Joseph Leffler, Benjamin Sivyer, W. Rowland Taylor, Kevin M. Wright

2020Cell Reports23 citationsDOIOpen Access PDF

Abstract

nGnG ACs also exhibit spatially restricted tracer coupling to bipolar cells (BCs) through gap junctions. This study identifies a genetic tool for investigating the two distinct AC subtypes, and it provides a model for studying synaptic communication and visual circuit function.

Topics & Concepts

NeuroscienceBiologyGABAergicExcitatory postsynaptic potentialPopulationAmacrine cellGlutamate receptorRetinaRibbon synapseCell biologyInhibitory postsynaptic potentialGeneticsSynaptic vesicleReceptorMembraneSociologyVesicleDemographyNeuroscience and Neuropharmacology ResearchRetinal Development and DisordersPhotoreceptor and optogenetics research
Gbx2 Identifies Two Amacrine Cell Subtypes with Distinct Molecular, Morphological, and Physiological Properties | Litcius