Incidence trend and disease burden of seven vaccine-preventable diseases in Shandong province, China, 2013–2017: Findings from a population-based observational study
Zhenwei Li, Chao-Nan Yin, Hai-Tao Wang, Wan-Yu Du, Wenjing Wang, Fuzhong Xue, Lin Zhao, Wu‐Chun Cao
Abstract
INTRODUCTION: Although vaccines provide a cost-effective solution to vaccine-preventable diseases (VPDs), the disease burden of VPDs is still very high in most parts of the world. METHODS: regression model. The disease burden was calculated using the disability-adjusted life years (DALYs). RESULTS: ). The top three causes of the disease burden as assessed with DALYs included tuberculosis, herpes zoster, and hepatitis B, with the rates of 72.21, 59.99, and 52.10 DALYs/100 000, respectively. The disease burden of influenza and herpes zoster were relatively high in people aged > 50 years, while highest DALYs of hepatitis B were found in young adults. CONCLUSION: Inequalities in the vaccine coverage by geography, socio-economic status, and targeted population contribute to the increasing incidence and high burden of VPDs and call for renewed and sustained immunization strategies in China.