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The impact and management of hyperemesis gravidarum: Current and future perspectives

Loïs M. van der Minnen, Iris J. Grooten, Caitlin Dean, Jone Trovik, Rebecca C. Painter

2025International Journal of Gynecology & Obstetrics7 citationsDOIOpen Access PDF

Abstract

Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy affecting around 1%-3% of pregnancies worldwide and is the most common reason for hospital admission in early pregnancy. HG can have lasting consequences for both pregnant individuals and their offspring. Current best-practice management includes symptomatic treatment with anti-emetic pharmacological treatment, rehydration if needed, and psychological support. There is a lack of high-quality evidence on treatment for HG. Future research should focus on understanding the cause, developing effective treatment, and so limiting the burden of disease on patients and healthcare systems.

Topics & Concepts

Hyperemesis gravidarumMedicineNauseaVomitingPregnancyIntensive care medicineLimitingObstetricsPediatricsSurgeryGeneticsBiologyMechanical engineeringEngineeringPregnancy and Medication ImpactElectrolyte and hormonal disordersGastroesophageal reflux and treatments
The impact and management of hyperemesis gravidarum: Current and future perspectives | Litcius