Pharmacokinetics of oral and subcutaneous methotrexate in red and white blood cells in patients with early rheumatoid arthritis: the methotrexate monitoring trial
Renske C. F. Hebing, Marry Lin, Maja Bulatović Ćalasan, Ittai B. Muller, Sohaila Mahmoud, Sandra G. Heil, Eduard A. Struys, Bart JF van den Bemt, Jos W. R. Twisk, Willem F. Lems, Michael T. Nurmohamed, Gerrit Jansen, Róbert de Jonge
Topics & Concepts
MedicineMethotrexateRheumatoid arthritisPharmacokineticsPeripheral blood mononuclear cellPharmacologyOral administrationWhite blood cellDistribution (mathematics)Internal medicineGastroenterologyImmunologyIn vitroBiochemistryChemistryMathematical analysisMathematicsRheumatoid Arthritis Research and TherapiesAcute Lymphoblastic Leukemia researchBiosimilars and Bioanalytical Methods