Litcius/Paper detail

Leukocytoclastic Vasculitis

Anila Vasireddy, Kanthilatha Pai, Varsha M. Shetty, Raviraja V Acharya, Kusugodlu Ramamoorthi, Akhila Doddamani, Sharath P Madhyastha

2022Sultan Qaboos University medical journal24 citationsDOIOpen Access PDF

Abstract

Scrub typhus is a disease endemic to the Indian subcontinent caused by the obligate intracellular pleomorphic organism, Orientia tsutsugamushi. Scrub typhus, among other acute febrile illnesses, manifests as prodromal symptoms of fever, malaise, myalgia and anorexia followed by a distinct maculopapular rash, hepatosplenomegaly and lymphadenopathy. We report the case of a patient presenting to tertiary care hospital in southern India in 2021 who developed a rare cutaneous vasculitis secondary to infection with Orientia tsutsugamushi. After performing the Weil-Felix test, a diagnostic titre of >1:640 against OXK was obtained. Furthermore, a skin biopsy was carried out which confirmed the diagnosis of leukocytoclastic vasculitis. The patient was treated with doxycycline and showed drastic improvement in his symptoms. Keywords: Scrub Typhus, Rickettsia; Vasculitis; Doxycycline; India.

Topics & Concepts

MedicineScrub typhusOrientia tsutsugamushimyalgiaDermatologyHepatosplenomegalyMaculopapular rashVasculitisMalaiseRashEscharPathologyImmunologyDiseaseVector-borne infectious diseasesMosquito-borne diseases and controlInflammasome and immune disorders