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Electrospun PCL‐Based Materials for Health‐Care Applications: An Overview

Teboho Clement Mokhena, Mandla B. Chabalala, Sivuyisiwe Mapukata, Asanda Mtibe, Lerato Hlekelele, Zamani E. D. Cele, Mokgaotsa Jonas Mochane, Bulelwa Ntsendwana, T.A. Nhlapo, Teboho P. Mokoena, Mokae Fanuel Bambo, Kgabo Phillemon Matabola, Suprakas Sinha Ray, Emmanuel Rotimi Sadiku, Katekani Shingange

2024Macromolecular Materials and Engineering41 citationsDOIOpen Access PDF

Abstract

Abstract Polycaprolactone (PCL) is one of the durable polymers with potential in a plethora of healthcare applications. Its biological properties, degradability, chemical properties, and mechanical properties can further be modified to manufacture desired products for modern biomedical applications. Electrospinning of PCL offers the opportunity to design treatment materials that resemble human tissues and facilitate regeneration at the target site. The resultant materials can also be modified by loading other active functional materials to broaden their applications. Herein, the recent advances in the preparation and modification of PCL‐based materials for healthcare applications are elucidated. The challenges and future trends for its application in modern biomedical applications are also outlined.

Topics & Concepts

PolycaprolactoneMaterials scienceElectrospinningNanotechnologyHuman healthBiocompatible materialPolymerBiomedical engineeringComposite materialEngineeringMedicineEnvironmental healthElectrospun Nanofibers in Biomedical Applicationsbiodegradable polymer synthesis and propertiesAdvanced Sensor and Energy Harvesting Materials
Electrospun PCL‐Based Materials for Health‐Care Applications: An Overview | Litcius