Self-assembly of hyaluronic acid-mediated tumor-targeting theranostic nanoparticles
Xiaoxuan Zhou, Chengbin He, Min Liu, Qingqing Chen, Lingjie Zhang, Xiaodan Xu, Hongxia Xu, Yue Qian, Feidan Yu, Yan Wu, Yuxin Han, Bing Xiao, Jianbin Tang, Hongjie Hu
Abstract
and strong photothermal therapy (PTT) effects with nearly complete tumor ablation under laser irradiation in vivo. HMDNs also showed effective clearance through kidneys, with no toxicity to important tissues. Therefore, HMDNs with superior imaging and PTT capability presented a new method to prepare tumor-targeting multifunctional nanotheranostics.
Topics & Concepts
Hyaluronic acidNanoparticleChemistryNanotechnologyAlbuminBiophysicsMaterials scienceBiochemistryMedicineBiologyAnatomyNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryDendrimers and Hyperbranched Polymers