Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition
Gianni Carraro, Justin Langerman, Shan Sabri, Zareeb Lorenzana, Arunima Purkayastha, Guangzhu Zhang, Bindu Konda, Cody J. Aros, Ben A. Calvert, Aleks Szymaniak, Emily Wilson, Michael Mulligan, Priyanka Bhatt, Junjie Lu, Preethi Vijayaraj, Changfu Yao, David W. Shia, Andrew Lund, Edo Israely, Tammy M. Rickabaugh, Jason Ernst, Martin Mense, Scott H. Randell, Eszter K. Vladar, Amy L. Ryan, Kathrin Plath, John E. Mahoney, Barry R. Stripp, Brigitte N. Gomperts
Topics & Concepts
Cystic fibrosisCystic fibrosis transmembrane conductance regulatorLungLung transplantationEpitheliumBiologyDiseaseAirwayTranscriptomeCellTransplantationPhenotypeRespiratory epitheliumImmunologyMedicinePathologyInternal medicineGeneGeneticsGene expressionSurgeryCystic Fibrosis Research AdvancesNeonatal Respiratory Health ResearchSingle-cell and spatial transcriptomics