Litcius/Paper detail

Covid-19: Antibody boost after third dose varies greatly by vaccine, study finds

Elisabeth Mahase

2021BMJ10 citationsDOI

Abstract

Covid-19: Antibody boost after third dose varies greatly by vaccine, study finds Elisabeth MahaseSix different covid-19 vaccines are safe and effective to use as booster doses in people who previously received the Oxford AstraZeneca or Pfizer BioNTech vaccines, but the antibody boost they provide varies substantially, a study has found. 1 The Cov-Boost trial looked at the safety, immune response, and side effects of seven vaccines when used as a third vaccine dose, often referred to as a booster dose-AstraZeneca, Curevac, Johnson & Johnson (Janssen), Moderna, Novavax, Pfizer, and Valneva, while a meningococcal conjugate vaccine was used as a control.The trial involved 2878 healthy participants over 30 years old who were split across 13 experimental and control arms-seven vaccines plus three at half dose and three control arms.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Ex vivoAntibodyImmunologyVirologyMedicineIn vivoBiologyInternal medicineBiotechnologyInfectious disease (medical specialty)DiseaseUrticaria and Related ConditionsCOVID-19 Clinical Research StudiesInflammasome and immune disorders