Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
Stephanie Stahnke, Hermann Döring, Charly Kusch, David J. J. de Gorter, Sebastian Dütting, Aleks Guledani, Irina Pleines, Michael Schnoor, Michael Sixt, Robert Geffers, Manfred Rohde, Mathias Müsken, Frieda Kage, Anika Steffen, Jan Faix, Bernhard Nieswandt, Klemens Rottner, Theresia E. B. Stradal
Topics & Concepts
PaxillinLamellipodiumCell biologyBiologyFocal adhesionPodosomeIntegrinCell adhesionPseudopodiaExtracellular matrixAdhesionCell migrationActinPhosphorylationCytoskeletonChemistryCellBiochemistryOrganic chemistryCell Adhesion Molecules ResearchCellular Mechanics and InteractionsPlatelet Disorders and Treatments