Litcius/Paper detail

The Pan-Immune Inflammation Value at Admission Predicts Postoperative in-hospital Mortality in Patients with Acute Type A Aortic Dissection

Xijing Yu, Yaqin Chen, Yanchun Peng, Liangwan Chen, Yanjuan Lin

2024Journal of Inflammation Research13 citationsDOIOpen Access PDF

Abstract

Purpose: The inflammatory response of the body is intimately linked to the quick onset and high in-hospital mortality of Acute Type A Aortic Dissection (ATAAD). The purpose of the study was to examine the connection between in-hospital mortality in patients with ATAAD upon admission and the Pan-Immune-Inflammation Value (PIV). Patients and Methods: 308 patients who were diagnosed with ATAAD between September 2018 and October 2021 at Fujian Provincial Center for Cardiovascular Medicine had their clinical data retrospectively examined. PIV was assessed at the time of study population admission, with in-hospital mortality serving as the main outcome measure. Patients were divided into two groups, the high PIV group (PIV > 1807.704) and the low PIV group (PIV < 1807.704), based on the PIV ROC curve and the best threshold of the Youden index. The clinical results of the two groups were then compared. Results: = 0.005) were independent risk factors for postoperative in-hospital mortality in ATAAD patients. Conclusion: Postoperative death in ATAAD patients was independently predicted by high PIV levels at admission. Patients should be informed about their preoperative inflammatory status and actively participate in prompt clinical decision-making and treatment.

Topics & Concepts

MedicineInflammationAortic dissectionImmune systemInternal medicineCardiologyGastroenterologySurgeryAortaImmunologyInflammatory Biomarkers in Disease PrognosisAortic Disease and Treatment ApproachesInflammation biomarkers and pathways