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Current Therapeutic Options in Aortic Stenosis

Marko T. Boskovski, Thomas G. Gleason

2021Circulation Research68 citationsDOIOpen Access PDF

Abstract

Aortic stenosis is the most common valvular disease requiring valve replacement. Valve replacement therapies have undergone progressive evolution since the 1960s. Over the last 20 years, transcatheter aortic valve replacement has radically transformed the care of aortic stenosis, such that it is now the treatment of choice for many, particularly elderly, patients. This review provides an overview of the pathophysiology, presentation, diagnosis, indications for intervention, and current therapeutic options for aortic stenosis.

Topics & Concepts

MedicineStenosisCardiologyInternal medicineValve replacementAortic valve replacementvalvular heart diseaseAortic valve stenosisAortic valveDiseaseSurgeryCurrent (fluid)RadiologyTherapeutic approachCardiac Valve Diseases and TreatmentsAortic Disease and Treatment ApproachesInfective Endocarditis Diagnosis and Management