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PROTACs: New method to degrade transcription regulating proteins

Bei-Chen Hu, Yirong Zhou, Dejuan Sun, Yueying Yang, Yang Liu, Xingzhou Li, Hua Li, Lixia Chen

2020European Journal of Medicinal Chemistry40 citationsDOIOpen Access PDF

Topics & Concepts

ProteasomeTranscription factorUbiquitin ligaseUbiquitinTranscription (linguistics)ChemistryRegulatorProtein degradationCell biologyProteolysisSmall moleculeTarget proteinComputational biologyBiologyBiochemistryGeneEnzymePhilosophyLinguisticsProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis
PROTACs: New method to degrade transcription regulating proteins | Litcius