The role of stabilizers and mechanical processes on physico-chemical and anti-inflammatory properties of methotrexate nanosuspensions
Aline Martins dos Santos, Andréía Bagliotti Meneguin, Bruno Fonseca‐Santos, Maurício Palmeira Chaves de Souza, Leonardo Miziara Barboza Ferreira, Rafael Miguel Sábio, Marlus Chorilli, Maria Palmira Daflon Gremião
Topics & Concepts
SonicationBioavailabilityZeta potentialParticle sizeDispersityPoloxamerMaterials sciencePoloxamer 407Pulmonary surfactantDissolutionChemical engineeringDynamic light scatteringIn vivoNanoparticleChemistryChromatographyNanotechnologyPharmacologyOrganic chemistryComposite materialPolymerPolymer chemistryBiotechnologyMedicineEngineeringBiologyCopolymerDrug Solubulity and Delivery SystemsAdvanced Drug Delivery SystemsAdvancements in Transdermal Drug Delivery