Gaps in Evidence for Risk Stratification for Sudden Cardiac Death in Hypertrophic Cardiomyopathy
Francesco Pelliccia, Bernard J. Gersh, Paolo G. Camici
Abstract
Sudden cardiac death (SCD) is the most dramatic and catastrophic complication of hypertrophic cardiomyopathy (HCM),1 with an annual rate of >1%.1 The identification of those patients most likely to benefit from prophylacticimplantable cardioverter defibrillators remains challenging in children and adults. The positive predictive value for appropriate discharges is low (≈20%), and the complication rates in this younger, active population is substantial, including lead problems, infections, inappropriate discharges, and psychological issues
Topics & Concepts
MedicineHypertrophic cardiomyopathySudden cardiac deathCardiomyopathyRisk stratificationInternal medicinePopulationCardiologySudden deathHeart failureEnvironmental healthCardiomyopathy and Myosin StudiesCardiac Structural Anomalies and RepairCardiac pacing and defibrillation studies