The Role of Thyroid Function in Alzheimer’s Disease
Feifei Ge, Donglin Zhu, Minjie Tian, Jingping Shi
Abstract
The thyroid gland is crucial for the regulation of metabolism, growth, and development of various tissues, organs, systems, including the central nervous system. Recent studies have implicated the role of thyroid dysfunction in the etiology of Alzheimer's disease (AD), while AD leads to a significant increase in the prevalence of thyroid dysfunction. In this review, we have analyzed the role of thyroid function in the pathophysiology of AD as well as its biomarkers. The present review aims to provide encouraging targets for early screening of AD risk factors and intervention strategies.
Topics & Concepts
ThyroidDiseaseMedicineThyroid functionThyroid dysfunctionEtiologyAlzheimer's diseaseCentral nervous systemPathophysiologyThyroid diseaseNeuroscienceBioinformaticsPathologyEndocrinologyBiologyThyroid Disorders and TreatmentsFolate and B Vitamins ResearchPharmacological Effects and Toxicity Studies