The development of an ultra-sensitive electrochemical immunosensor using a PPyr-NHS functionalized disposable ITO sheet for the detection of interleukin 6 in real human serums
Elif Burcu Aydın, Muhammet Aydın, Mustafa Kemal Sezgintürk
Abstract
A label-free biosensor based on poly(pyrrole <italic>N</italic>-hydroxy succinimide) polymer modified ITO electrode was developed for sensitive detection of interleukin 6 antigen. Under optimized conditions, it had a wide detection range (0.03–22.5 pg mL<sup>−1</sup>).
Topics & Concepts
ChemistrySuccinimideBiosensorPyrroleElectrodeAmperometryChromatographyElectrochemistryCombinatorial chemistryNanotechnologyOrganic chemistryBiochemistryMaterials sciencePhysical chemistryAdvanced biosensing and bioanalysis techniquesConducting polymers and applicationsElectrochemical sensors and biosensors