Switchable Membrane Remodeling and Antifungal Defense by Metamorphic Chemokine XCL1
Acacia F. Dishman, Michelle W. Lee, Jaime de Anda, Ernest Y. Lee, Jie He, Anna R. Huppler, Gerard C. L. Wong, Brian F. Volkman
Abstract
, in contrast to the usual mode of antifungal defense which requires Th17 mediated cell-based responses. These observations suggest that metamorphic XCL1 is capable of a versatile multimodal form of antimicrobial defense.
Topics & Concepts
ChemokineCell biologyChemokine receptorAntimicrobial peptidesBiologyChemistryBiophysicsReceptorBiochemistryPeptideAntimicrobial Peptides and ActivitiesImmune Response and InflammationPolydiacetylene-based materials and applications