New Strategies in Enhancing Spinal Fusion
Yoshihiro Katsuura, Karim Shafi, Chelsie Jacques, Sohrab Virk, Sravisht Iyer, Matthew E. Cunningham
2020HSS Journal® The Musculoskeletal Journal of Hospital for Special Surgery19 citationsDOIOpen Access PDF
Abstract
The biologic steps involved in creating a bony fusion between adjacent segments of the spine are a complex and highly coordinated series of events. There have been significant advancements in bone grafts and bone graft substitutes in order to augment spinal fusion. While autologous bone grafting remains the gold standard, allograft bone grafting, synthetic bone graft substitutes, and bone graft enhancers are appropriate in certain clinical situations. This article provides an overview of the basic biology of spinal fusion and strategies for enhancing fusion through innovations in bone graft material.
Topics & Concepts
Spinal fusionMedicineBone graftingBone transplantationGraftingOrthopedic surgerySurgeryChemistryPolymerOrganic chemistryBone Tissue Engineering MaterialsSpine and Intervertebral Disc PathologyOrthopaedic implants and arthroplasty