Sarcoma microenvironment cell states and ecosystems are associated with prognosis and predict response to immunotherapy
Ajay Subramanian, Neda Nemat‐Gorgani, Timothy John Ellis-Caleo, David G.P. van IJzendoorn, Timothy J. Sears, Anish Somani, Bogdan Luca, Maggie Zhou, Martina Bradić, Ileana A. Torres, Eniola Oladipo, Christin New, Deborah Kenney, Raffi S. Avedian, Robert Steffner, Michael S. Binkley, David G. Mohler, William D. Tap, Sandra P. D’Angelo, Matt van de Rijn, Kristen N. Ganjoo, Nam Q. Bui, Gregory W. Charville, Aaron M. Newman, Everett J. Moding
Topics & Concepts
Stromal cellImmunotherapySarcomaImmune systemBiologyTumor microenvironmentTranscriptomeEcotypeCellCancer researchSoft tissue sarcomaComputational biologyMedicineBioinformaticsImmunologyPathologyEcologyGeneGene expressionGeneticsSarcoma Diagnosis and TreatmentCancer Cells and MetastasisCancer Immunotherapy and Biomarkers