Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer
Emily J. Faivre, Keith F. McDaniel, Daniel H. Albert, Srinivasa R. Mantena, Joshua P. Plotnik, Denise Wilcox, Lu Zhang, Mai H. Bui, George S. Sheppard, Le Wang, Vasudha Sehgal, Xiaoyu Lin, Xiaoli Huang, Xin Lü, Tamar Uziel, Paul Hessler, Lloyd T. Lam, Richard J. Bellin, Gaurav Mehta, Steve Fidanze, John K. Pratt, Dachun Liu, Lisa Hasvold, Chaohong Sun, Sanjay C. Panchal, John Nicolette, Stacey Fossey, Chang H. Park, Kenton L. Longenecker, L. Bigelow, Maricel Torrent, Saul H. Rosenberg, Warren M. Kati, Yu Shen
Topics & Concepts
BromodomainBRD4BET inhibitorEpigeneticsChemistryPharmacologyIn vivoCancer researchBiologyBiochemistryGeneticsGeneProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsCancer-related gene regulation