Litcius/Paper detail

Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer

Emily J. Faivre, Keith F. McDaniel, Daniel H. Albert, Srinivasa R. Mantena, Joshua P. Plotnik, Denise Wilcox, Lu Zhang, Mai H. Bui, George S. Sheppard, Le Wang, Vasudha Sehgal, Xiaoyu Lin, Xiaoli Huang, Xin Lü, Tamar Uziel, Paul Hessler, Lloyd T. Lam, Richard J. Bellin, Gaurav Mehta, Steve Fidanze, John K. Pratt, Dachun Liu, Lisa Hasvold, Chaohong Sun, Sanjay C. Panchal, John Nicolette, Stacey Fossey, Chang H. Park, Kenton L. Longenecker, L. Bigelow, Maricel Torrent, Saul H. Rosenberg, Warren M. Kati, Yu Shen

2020Nature405 citationsDOI

Topics & Concepts

BromodomainBRD4BET inhibitorEpigeneticsChemistryPharmacologyIn vivoCancer researchBiologyBiochemistryGeneticsGeneProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsCancer-related gene regulation
Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer | Litcius