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Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis

Suzanne C. Edavettal, Pilar Cejudo-Martı́n, B. Dasgupta, Danlin Yang, Matthew D. Buschman, Derrick L. Domingo, Kristof Van Kolen, Pharavee Jaiprasat, Renata E. Gordon, Keith Schutsky, Brian Geist, Natalie Taylor, Camille Helene Soubrane, Elisabeth Van Der Helm, Ann LaCombe, Zemeda Ainekulu, Eilyn R. Lacy, Jason Aligo, Jason Ho, Yingbo He, Peter F. Lebowitz, James T Patterson, Justin M. Scheer, Sanjaya Singh

2022Med80 citationsDOI

Topics & Concepts

TranscytosisTransferrin receptorBlood–brain barrierAntibodyPhagocytosisReceptorImmune systemMyeloidImmunologyMedicineBiologyNeuroscienceCentral nervous systemEndocytosisInternal medicineMonoclonal and Polyclonal Antibodies ResearchBarrier Structure and Function StudiesProtein purification and stability
Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis | Litcius