Identification of novel dipeptidyl peptidase IV and α-glucosidase inhibitory peptides from <i>Tenebrio molitor</i>
Fernando Rivero‐Pino, Antonio Guadix, Emilia M. Guadix
Abstract
). Numerous novel peptides were identified from the most bioactive fractions, and based on the molecular features usually described for these peptides, some of them are suggested to be the bioactive peptides responsible for the inhibition observed (e.g. APVAH for DPP-IV inhibition and CSR for α-glucosidase inhibition). Hence, these insect protein hydrolysates or their purified fractions could be used as ingredients for regulation of the glycaemic index.
Topics & Concepts
Dipeptidyl peptidaseDipeptidyl peptidase-4BiochemistryEnzymePeptideEnzymatic hydrolysisChemistryBiologyEndocrinologyDiabetes mellitusType 2 diabetesInsect Utilization and EffectsProtein Hydrolysis and Bioactive PeptidesNeurobiology and Insect Physiology Research