Kaempferol ameliorated alcoholic liver disease through inhibiting hepatic bile acid synthesis by targeting intestinal FXR-FGF15 signaling
Li Xiao, Guangfu Xu, Silong Chen, Yumin He, Fan Peng, Chengfu Yuan
Topics & Concepts
Bile acidAlcoholic liver diseaseEnterohepatic circulationInternal medicineG protein-coupled bile acid receptorPharmacologyChemistryFarnesoid X receptorEndocrinologyMedicineBiochemistryCirrhosisTranscription factorNuclear receptorGeneFibroblast Growth Factor ResearchDrug Transport and Resistance MechanismsLiver physiology and pathology