Microsclerodermins N and O, cytotoxic cyclic peptides containing a p-ethoxyphenyl moiety from a deep-sea marine sponge Pachastrella sp.
Tian Tian, Kentaro Takada, Yuji Ise, Susumu Ohtsuka, Shigeru Okada, Shigeki Matsunaga
Topics & Concepts
MoietyChemistrySpongeStereochemistryResidue (chemistry)StereocenterHeLaDerivatizationCytotoxic T cellAmino acidBiochemistryOrganic chemistryIn vitroHigh-performance liquid chromatographyCatalysisBiologyEnantioselective synthesisBotanyMarine Sponges and Natural ProductsEnzyme function and inhibitionMicrobial Natural Products and Biosynthesis