Litcius/Paper detail

Nearly Complete Genome Sequence of Brugia malayi Strain FR3

Alan Tracey, Jeremy M. Foster, Michael Paulini, Alexandra Grote, John Mattick, Yu-Chih Tsai, Matthew Chung, James A. Cotton, Tyson A. Clark, Adam Geber, Nancy Holroyd, Jonas Korlach, Silvia Libro, Sara Lustigman, Michelle L. Michalski, Matthew B. Rogers, Alan Twaddle, Julie C. Dunning Hotopp, Matthew Berriman, Elodie Ghedin

2020Microbiology Resource Announcements21 citationsDOIOpen Access PDF

Abstract

Lymphatic filariasis affects ∼120 million people and can result in elephantiasis and hydrocele. Here, we report the nearly complete genome sequence of the best-studied causative agent of lymphatic filariasis, Brugia malayi . The assembly contains four autosomes, an X chromosome, and only eight gaps but lacks a contiguous sequence for the known Y chromosome.

Topics & Concepts

Brugia malayiBiologyStrain (injury)GenomeGeneticsSequence (biology)Whole genome sequencingGeneZoologyHelminthsFilariasisAnatomyPlant tissue culture and regenerationPlant Parasitism and ResistanceBiochemical and Structural Characterization