A sustainable and scalable multicomponent continuous flow process to access fused imidazoheterocycle pharmacophores
Blake J. M. Baker, William J. Kerr, David M. Lindsay, Vipulkumar K. Patel, Darren L. Poole
Abstract
A sustainable flow process has been established for the application of the Gröebke–Blackburn–Bienaymé reaction for access to high-value fused heteroaromatics.
Topics & Concepts
PharmacophoreScalabilityProcess (computing)Combinatorial chemistryContinuous flowFlow (mathematics)Flow chemistryChemistryValue (mathematics)Computer scienceProcess engineeringBiochemical engineeringMathematicsStereochemistryDatabaseEngineeringGeometryMachine learningOperating systemInnovative Microfluidic and Catalytic Techniques InnovationNanomaterials for catalytic reactionsOxidative Organic Chemistry Reactions