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Recent Advances in p53

Gabriella D’Orazi

2021Biomolecules27 citationsDOIOpen Access PDF

Abstract

Tumor suppressor protein p53 (TP53) is a key transcription factor that, in response to various stress signals, regulates numerous genes involved in a broad range of cellular functions including DNA repair, apoptosis, cell cycle arrest, senescence, metabolism, etc [...].

Topics & Concepts

SuppressorTranscription factorDNA damageP53 proteinSenescenceCell cycle checkpointDNA repairBiologyCell biologyCell cycleApoptosisTranscription (linguistics)GeneCellular senescenceCellular metabolismComputational biologyDNAGeneticsMetabolismPhenotypeBiochemistryLinguisticsPhilosophyCancer-related Molecular PathwaysMicroRNA in disease regulationRNA modifications and cancer
Recent Advances in p53 | Litcius