Tumor hypoxia: an important regulator of tumor progression or a potential modulator of tumor immunogenicity?
Goutham Hassan Venkatesh, Raefa Abou Khouzam, Walid El‐Sayed, Nagwa Ahmed Zeinelabdin, Stéphane Terry, Salem Chouaı̈b
Abstract
Hypoxia in the tumor microenvironment has been shown to be a strong indicator of tumor aggressiveness, metastases, and promotes cancer progression.1 Several studies have indicated that tumor hypoxi...
Topics & Concepts
RegulatorImmunogenicityHypoxia (environmental)Tumor hypoxiaCancer researchMedicineTumor progressionBiologyImmunologyCancerChemistryImmune systemInternal medicineRadiation therapyGeneOrganic chemistryOxygenBiochemistryCancer, Hypoxia, and MetabolismCancer Research and TreatmentsRNA modifications and cancer