Autonomous Treatment of Bacterial Infections <i>in Vivo</i> Using Antimicrobial Micro- and Nanomotors
Xavier Arqué, Marcelo D. T. Torres, Tania Patiño, Andreia Boaro, Samuel Sánchez, César de la Fuente‐Núñez
Abstract
in a clinically relevant abscess infection mouse model. In summary, our motors combine navigation, catalytic conversion, and bactericidal capacity to deliver antimicrobial payloads to specific infection sites. This technology represents a much-needed tool to direct therapeutics to their target to help combat drug-resistant infections.
Topics & Concepts
AntimicrobialAntibiotic resistanceAntibioticsIn vivoMicrobiologyPathogenic bacteriaAntimicrobial peptidesDrug resistanceBacteriaBiologyBiotechnologyGeneticsMicro and Nano RoboticsMolecular Communication and NanonetworksLipid Membrane Structure and Behavior